CLAIM CARD
Mechanistically, CoQ10's anti-inflammatory effects are plausibly linked to its role in mitochondrial electron transport and as a lipid-soluble antioxidant, which may reduce oxidative stress-driven NF-κB activation and downstream cytokine production. Jorat 2019's meta-analysis in coronary artery disease patients demonstrated pooled reductions in inflammatory and oxidative stress biomarkers with P < 0.001, P < 0.001, P = 0.001, and P < 0.001 across different markers, supporting a mechanistic link between CoQ10 repletion and reduced inflammation in cardiovascular contexts. Mojaver 2025 reported a dose of 600 mg/day.
Evidence grade: exploratory
Contradiction status: none
Publication: b8dee5f7-0023-4af5-bacc-446de915555a
Provenance: Derivation Web chain
Citation Support
source_1Xu 2024source_2Spiegeleer 2025source_3Shang 2024source_4Alehagen 2020source_5Phan 2020