RESEARKA

The cited A/B receipts support a specific working claim: rapamycin led to a 217% and 106% increase of M1 (CD45+CD64+CD206−) ATMs in females; rapamycin led to a 217% and 106% increase of M1 (CD45+CD64+CD206−) ATMs in females and males, respectively. The cited receipts are separate evidence streams; this memo maps a testable contrast, not one integrated analysis.

Citation Support

• source_1 Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging
• source_2 Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
• source_3 Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
• source_4 Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
• source_5 Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer