RESEARKA

`fact_id=135477` (`A_core`) — rapamycin led to a 56% increase of CD45+ leukocytes in gWAT, where the majority of these are ATMs doi=10.1093/gerona/glz177

Citation Support

• source_1 Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging
• source_2 Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
• source_3 Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
• source_4 Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
• source_5 Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer