RESEARKA

_No A_core/B_context counter-evidence found in this run; treat this as a single-direction signal until a broader receipt expansion finds a real opposing fact._

Citation Support

• source_1 Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging
• source_2 Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
• source_3 Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
• source_4 Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
• source_5 Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer