RESEARKA

The corpus for immune and inflammatory outcomes includes five reference papers examining aspirin's effects through diverse study designs and populations. A clinical RCT by Areia 2025 enrolled thirty-two pregnant women receiving low-dose aspirin (LDA) to evaluate immune cell modulation, with analyses of natural killer (NK) cell subsets performed at the second trimester versus four weeks after LDA initiation. Observational data from Gwenzi 2026 examined personalized vitamin D3 supplementation effects on inflammation in colorectal cancer patients who underwent surgery within the past year, while Sattui 2026 described the ongoing Reducing Inflammation for Greater Health Trial (RIGHT), which will enroll participants aged 70 years and older with low to moderate physical function. The remaining evidence comprises systematic reviews and meta-analyses: Zhang 2026 evaluated the systemic immune-inflammation index (SII) as a predictor of atrial fibrillation recurrence, and He 2026 assessed fecal microbiota transplantation effects on liver inflammation indicators in metabolic-associated fatty liver disease.

Citation Support

• source_1 Flensted-Jensen 2025
• source_2 Saeed 2026
• source_3 Zhu 2026
• source_4 Navarese 2026
• source_5 Yan 2024