CLAIM CARD
fact_id=12624: increased EC contributions to lesions via EC-to-mesenchymal transition (EndoMT) by 60% in advanced atherosclerotic Apoe-/- mice fed western diet; intervention: ABT-263 at 100 mg/kg or 50 mg/kg; source DOI: 10.1172/jci.insight.173863
Evidence grade: exploratory
Contradiction status: none
Publication: b18dacf3-a86e-4d0d-b54f-ea476005c515
Provenance: Derivation Web chain
Citation Support
source_1Treatment of advanced atherosclerotic mice with ABT-263 reduced indices of plaque stability and increased mortalitysource_2Irisin Correlates Positively With BMD in a Cohort of Older Adult Patients and Downregulates the Senescent Marker p21 in Osteoblastssource_3Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescencesource_4Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice