RESEARKA

The curated corpus is dominated by observational cohort designs, with no long-term mortality-focused randomized controlled trial of aerobic exercise in non-diabetic older adults included. Outcomes related to all-cause mortality and hard cardiovascular events were addressed only indirectly — for example, Moore 2012 and Mok 2019 reported pooled cohort associations between leisure-time physical activity and mortality, but neither constituted a controlled intervention trial. Consequently, causal claims linking aerobic exercise to survival benefit in this synthesis remain inferred rather than demonstrated. This gap is clinically significant because mortality reduction is often the ultimate justification for exercise prescription in aging guidelines, yet the corpus lacks the trial-level evidence needed to confirm or quantify that benefit.

Citation Support

• source_1 PMC10673924 prospective association of occupational and leisure time phy
• source_2 PMC8308714 eating speed physical activity and cardiorespiratory fitness
• source_3 PMC9876872 effects of concurrent strength and endurance training on mea
• source_4 PMC8637860 5 years of exercise intervention did not benefit cognition c
• source_5 PMC9095946 whole body and muscle responses to aerobic exercise training