{"publication_id":"6ef37c0d-3324-4ba9-b7da-5e747c7ce46f","traces":[{"claim_id":"claim_1","claim":"Synthesis:** Receipt 1 reports Cold-water immersion after training sessions: effects on fiber type-specific adaptations in muscle K+ transport proteins to sprint-interval training in men; excerpt: Training increased ( P < 0.05) the abundance of α1 and β3 in both fiber types and β1 in type-II fibers and decreased FXYD1 in type-I fibers, whereas α2 and α3 abundance was not altered by training ( P > 0.05). in a human study. Receipt 2 reports Does Cold-Water Immersion After Strength Training Attenuate Training Adaptation?; excerpt: RESULTS No significant effects were found for strength or jump performance. in a human study. The comparison is bounded to cold water immersion, and should not be read as advice, settled science, or a broad class claim.","citation_support":[],"candidate_sources":[{"study":"Cold-water immersion after training sessions: effects on fiber type-specific adaptations in muscle K+ transport proteins to sprint-interval training in men.","year":2018,"doi":"10.1152/japplphysiol.00259.2018","url":"https://www.semanticscholar.org/paper/257f4ff82a4dd9a636e6c6c6dca901c278c2d370","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary","excerpt":"Effects of regular use of cold-water immersion (CWI) on fiber type-specific adaptations in muscle K+ transport proteins to intense training, along with their relationship to changes in mRNA levels after the first training session, were investigated in humans. Nineteen recreationally active men (24 ± 6 yr, 79.5 ± 10.8 kg, 44.6 ± 5.8 ml·kg-1·min-1) completed six weeks of sprint-interval cycling, either without (passive rest; CON) or with training sessions followed by CWI (15 min at 10°C; COLD). Muscle biopsies were obtained before and after training to determine abundance of Na+, K+-ATPase isoforms (α1-3, β1-3) and phospholemman (FXYD1) and after recovery treatments (+0 h and +3 h) on the first day of training to measure mRNA content. Training increased ( P < 0.05) the abundance of α1 and β3 in both fiber types and β1 in type-II fibers and decreased FXYD1 in type-I fibers, whereas α2 and α","source_id":"source_1","support_kind":"candidate_source_row"},{"study":"Does Cold-Water Immersion After Strength Training Attenuate Training Adaptation?","year":2020,"doi":"10.1123/ijspp.2019-0965","url":"https://www.semanticscholar.org/paper/79a3b51fba09c72b990d0effe27e5b824c523f3e","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary","excerpt":"PURPOSE Cold-water immersion is increasingly used by athletes to support performance recovery. Recently, however, indications have emerged suggesting that the regular use of cold-water immersion might be detrimental to strength training adaptation. METHODS In a randomized crossover design, 11 participants performed two 8-week training periods including 3 leg training sessions per week, separated by an 8-week \"wash out\" period. After each session, participants performed 10 minutes of either whole-body cold-water immersion (cooling) or passive sitting (control). Leg press 1-repetition maximum and countermovement jump performance were determined before (pre), after (post) and 3 weeks after (follow-up) both training periods. Before and after training periods, leg circumference and muscle thickness (vastus medialis) were measured. RESULTS No significant effects were found for strength or jump","source_id":"source_2","support_kind":"candidate_source_row"}]},{"claim_id":"claim_2","claim":"Interpretation:** The supported claim is not universal failure; it is that the Receipt 1 signal does not automatically transfer to the Receipt 2 population, modality, and endpoint bundle.","citation_support":[],"candidate_sources":[{"study":"Cold-water immersion after training sessions: effects on fiber type-specific adaptations in muscle K+ transport proteins to sprint-interval training in men.","year":2018,"doi":"10.1152/japplphysiol.00259.2018","url":"https://www.semanticscholar.org/paper/257f4ff82a4dd9a636e6c6c6dca901c278c2d370","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary","excerpt":"Effects of regular use of cold-water immersion (CWI) on fiber type-specific adaptations in muscle K+ transport proteins to intense training, along with their relationship to changes in mRNA levels after the first training session, were investigated in humans. Nineteen recreationally active men (24 ± 6 yr, 79.5 ± 10.8 kg, 44.6 ± 5.8 ml·kg-1·min-1) completed six weeks of sprint-interval cycling, either without (passive rest; CON) or with training sessions followed by CWI (15 min at 10°C; COLD). Muscle biopsies were obtained before and after training to determine abundance of Na+, K+-ATPase isoforms (α1-3, β1-3) and phospholemman (FXYD1) and after recovery treatments (+0 h and +3 h) on the first day of training to measure mRNA content. Training increased ( P < 0.05) the abundance of α1 and β3 in both fiber types and β1 in type-II fibers and decreased FXYD1 in type-I fibers, whereas α2 and α","source_id":"source_1","support_kind":"candidate_source_row"},{"study":"Does Cold-Water Immersion After Strength Training Attenuate Training Adaptation?","year":2020,"doi":"10.1123/ijspp.2019-0965","url":"https://www.semanticscholar.org/paper/79a3b51fba09c72b990d0effe27e5b824c523f3e","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary","excerpt":"PURPOSE Cold-water immersion is increasingly used by athletes to support performance recovery. Recently, however, indications have emerged suggesting that the regular use of cold-water immersion might be detrimental to strength training adaptation. METHODS In a randomized crossover design, 11 participants performed two 8-week training periods including 3 leg training sessions per week, separated by an 8-week \"wash out\" period. After each session, participants performed 10 minutes of either whole-body cold-water immersion (cooling) or passive sitting (control). Leg press 1-repetition maximum and countermovement jump performance were determined before (pre), after (post) and 3 weeks after (follow-up) both training periods. Before and after training periods, leg circumference and muscle thickness (vastus medialis) were measured. RESULTS No significant effects were found for strength or jump","source_id":"source_2","support_kind":"candidate_source_row"}]},{"claim_id":"claim_3","claim":"Evidence gap:** The missing study is one matched design with the same population, protocol, dose, duration, and endpoint.","citation_support":[],"candidate_sources":[{"study":"Cold-water immersion after training sessions: effects on fiber type-specific adaptations in muscle K+ transport proteins to sprint-interval training in men.","year":2018,"doi":"10.1152/japplphysiol.00259.2018","url":"https://www.semanticscholar.org/paper/257f4ff82a4dd9a636e6c6c6dca901c278c2d370","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary","excerpt":"Effects of regular use of cold-water immersion (CWI) on fiber type-specific adaptations in muscle K+ transport proteins to intense training, along with their relationship to changes in mRNA levels after the first training session, were investigated in humans. Nineteen recreationally active men (24 ± 6 yr, 79.5 ± 10.8 kg, 44.6 ± 5.8 ml·kg-1·min-1) completed six weeks of sprint-interval cycling, either without (passive rest; CON) or with training sessions followed by CWI (15 min at 10°C; COLD). Muscle biopsies were obtained before and after training to determine abundance of Na+, K+-ATPase isoforms (α1-3, β1-3) and phospholemman (FXYD1) and after recovery treatments (+0 h and +3 h) on the first day of training to measure mRNA content. Training increased ( P < 0.05) the abundance of α1 and β3 in both fiber types and β1 in type-II fibers and decreased FXYD1 in type-I fibers, whereas α2 and α","source_id":"source_1","support_kind":"candidate_source_row"},{"study":"Does Cold-Water Immersion After Strength Training Attenuate Training Adaptation?","year":2020,"doi":"10.1123/ijspp.2019-0965","url":"https://www.semanticscholar.org/paper/79a3b51fba09c72b990d0effe27e5b824c523f3e","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary","excerpt":"PURPOSE Cold-water immersion is increasingly used by athletes to support performance recovery. Recently, however, indications have emerged suggesting that the regular use of cold-water immersion might be detrimental to strength training adaptation. METHODS In a randomized crossover design, 11 participants performed two 8-week training periods including 3 leg training sessions per week, separated by an 8-week \"wash out\" period. After each session, participants performed 10 minutes of either whole-body cold-water immersion (cooling) or passive sitting (control). Leg press 1-repetition maximum and countermovement jump performance were determined before (pre), after (post) and 3 weeks after (follow-up) both training periods. Before and after training periods, leg circumference and muscle thickness (vastus medialis) were measured. RESULTS No significant effects were found for strength or jump","source_id":"source_2","support_kind":"candidate_source_row"}]}]}