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Atomic claims extracted from accepted Researka artifacts, with source support, contradiction state, and provenance links when available.

Filtered to publication 40ee40b9-6c56-499a-8ac8-120a3efd2edf

exploratory

The cited A/B receipts support a specific working claim: rapamycin led to a 217% and 106% increase of M1 (CD45+CD64+CD206−) ATMs in females; rapamycin led to a 217% and 106% increase of M1 (CD45+CD64+CD206−) ATMs in females and males, respectively. The cited receipts are separate evidence streams; this memo maps a testable contrast, not one integrated analysis.

Contradiction: none

Sources: 5

exploratory

Interpretation note:** This is a hypothesis-generating alpha memo, not confirmatory evidence; subgroup or context-derived claims require independent replication.

Contradiction: none

Sources: 5

exploratory

`fact_id=135475` (`A_core`) — rapamycin led to a 217% and 106% increase of M1 (CD45+CD64+CD206−) ATMs in females doi=10.1093/gerona/glz177

Contradiction: none

Sources: 5

exploratory

`fact_id=135476` (`A_core`) — rapamycin led to a 217% and 106% increase of M1 (CD45+CD64+CD206−) ATMs in females and males, respectively doi=10.1093/gerona/glz177

Contradiction: none

Sources: 5

exploratory

`fact_id=135477` (`A_core`) — rapamycin led to a 56% increase of CD45+ leukocytes in gWAT, where the majority of these are ATMs doi=10.1093/gerona/glz177

Contradiction: none

Sources: 5

exploratory

`fact_id=166319` (`A_core`) — Metformin (0.1%) combined with rapamycin (14 ppm) robustly extended lifespan, suggestive of an added benefit. doi=10.1111/acel.12496

Contradiction: none

Sources: 5

exploratory

_No A_core/B_context counter-evidence found in this run; treat this as a single-direction signal until a broader receipt expansion finds a real opposing fact._

Contradiction: none

Sources: 5

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